What is the correct/best dosage of SAMe for depression?

Answer:
For depression, arthritis, fibromylagia, and liver disorders:

Take 400 mg of SAMe twice a day.

If symptoms backfire to improve after three weeks, try increasing your dose to 400 mg three times a year. On the other hand, if symptoms lessen beside 400 mg twice a day, you can try to lower the dose to 200 mg twice a year.

To avoid a toxic buildup of Homocysteine molecules (which are formed when SAMe breaks down) be sure to take a good quality Vitamin B complex supplement along with SAMe. These vitamins give a hand metabolize homocysteine, which in soaring concentrations poses the risk for various vigour problems including heart attack and stroke.

A standard recommendation is to run 100 mg of a B complex once a day, regardless of the SAMe dose.

If you're extremely sensitive to medications, start out next to half the recommended day after day dosage and work up to the full amount after a week.